α-Glucosidase Inhibitory Constituents from Ficus bengalensis
Received 07 Mar, 2015 |
Accepted 22 Sep, 2015 |
Published 07 Dec, 2015 |
Chromatographic purification of the methanolic extract of the aerial roots of Ficus bengalensis resulted the purifiaction of 3β-acetoxyurs-9(11),12-diene (1), a new triterpene together with lupeol (2), lupeol acetate (3), conrauidienol (4), β-sitosterol (5), alpinum isoflavone (6), methyl 4-hydroxybenzoate (7), 4-hydroxymellein (8), 4-hydroxybenzoic acid (9), p-coumaric acid (10), oleanolic acid (11) and β-sitosterol 3-O-β-D-glucopyranoside (12). These compounds (1-12) were characterized by using 1D- (1H,13C) and 2D-NMR (HMQC, HMBC, COSY, NOESY) spectroscopy and mass spectrometry (EI-MS, HR-EI-MS, FAB-MS, HRFAB-MS), and in comparison with the data reported for related compounds in literature. These isolates (1-12) showed inhibitory activity against enzyme α-glucosidase with IC50 values ranging between 26.3-297.7 µM.
How to Cite this paper?
APA-7 Style
Naveed,
M.A., Riaz,
N., Saleem,
M., Jabeen,
B., Ashraf,
M., Alam,
U., Jabbar,
A. (2015). α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pakistan Journal of Chemistry, 5(1), 42-49. https://doi.org/10.15228/2015.v05.i01.p07
ACS Style
Naveed,
M.A.; Riaz,
N.; Saleem,
M.; Jabeen,
B.; Ashraf,
M.; Alam,
U.; Jabbar,
A. α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pak. J. Chem. 2015, 5, 42-49. https://doi.org/10.15228/2015.v05.i01.p07
AMA Style
Naveed
MA, Riaz
N, Saleem
M, Jabeen
B, Ashraf
M, Alam
U, Jabbar
A. α-Glucosidase Inhibitory Constituents from Ficus bengalensis. Pakistan Journal of Chemistry. 2015; 5(1): 42-49. https://doi.org/10.15228/2015.v05.i01.p07
Chicago/Turabian Style
Naveed, M., A., N. Riaz, M. Saleem, B. Jabeen, M. Ashraf, U. Alam, and A. Jabbar.
2015. "α-Glucosidase Inhibitory Constituents from Ficus bengalensis" Pakistan Journal of Chemistry 5, no. 1: 42-49. https://doi.org/10.15228/2015.v05.i01.p07
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