Research Article | Open Access

Irinotecan and Bevacizumab in Glioblastoma-A Review

    M.T. Shahid

    Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan

    S. Khair-ul-Bariyah

    Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan


Received
10 Mar, 2014
Accepted
01 Sep, 2014
Published
01 Dec, 2014

Glioblastoma is a common brain tumor having comparatively poor prognosis. Bevacizumab and irinotecan are found to be
effective in the treatment of recurrent glioblastoma. The present review covers investigations made on the mentioned drugs in the
past decade. As compared to other chemotherapeutic agents, the drugs have shown greater activity and overall survival when used
as monotherapeutic agents or in combination with other drugs. Still some work needs to be done in establishing clear role of both
the drugs in newly diagnosed glioblastoma, especially, role of irinotecan needs clarity.

How to Cite this paper?


APA-7 Style
Shahid, M.T., Khair-ul-Bariyah, S. (2014). Irinotecan and Bevacizumab in Glioblastoma-A Review. Pakistan Journal of Chemistry, 4(1), 1-5. https://doi.org/10.15228/2014.v04.i01.p01

ACS Style
Shahid, M.T.; Khair-ul-Bariyah, S. Irinotecan and Bevacizumab in Glioblastoma-A Review. Pak. J. Chem. 2014, 4, 1-5. https://doi.org/10.15228/2014.v04.i01.p01

AMA Style
Shahid MT, Khair-ul-Bariyah S. Irinotecan and Bevacizumab in Glioblastoma-A Review. Pakistan Journal of Chemistry. 2014; 4(1): 1-5. https://doi.org/10.15228/2014.v04.i01.p01

Chicago/Turabian Style
Shahid, M., T., and S. Khair-ul-Bariyah. 2014. "Irinotecan and Bevacizumab in Glioblastoma-A Review" Pakistan Journal of Chemistry 4, no. 1: 1-5. https://doi.org/10.15228/2014.v04.i01.p01